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  • Generic Rapamune (Sirolimus, Rapamycin)

Generic Rapamune (Sirolimus, Rapamycin)

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Sirolimus, a new kind of immunosuppressant medicine is used for the kidney transplant patients. However, now it is used for all transplant patients. It is available as unit dose sachets as well as multi-dose bottles. During the process of transplant rejection, the organ transplanted produces lymphocytes in the body which multiply to respond to certain molecules. This medicine restricts the multiplication of lymphocytes in response to these. Immunosuppressants like tacrolimus and cyclosporine, work on the molecules, instead of working on the lymphocytes. It can be given with other immunosuppressants to have a more benefits The interaction of sirolimus with other immunosuppressants can have a combined effect that is even more beneficial. It is often called as a synergistic effect.

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  • Product Code: Generic Rapamune (Sirolimus, Rapamycin)
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Sirolimus Dosage

  • Sirolimus should be mixed with two ounces of either orange juice or water and shaken vigorously just prior to administration. To ensure that the entire drug dose is taken, refill the cup used with four more ounces of either orange juice or water and have your child drink that as well.
  • The dose should be taken four hours after either cyclosporine or tacrolimus doses. Sirolimus must be stored in the refrigerator.
  • While your child is on this medication and for 24 hours afterwards, he or she should drink extra fluids and empty your bladder regularly. This helps the kidneys remove the drug from his or her body, and avoids some of the side effects.

Sirolimus Precautions

  • When an immunosuppressive medicine is used, and especially combined, there is an increased risk of infection and the possibility of a lymphocyte disorder that can lead to cancer.
  • Although it is not dangerous to the kidneys, but their function needs to be should be monitored when used with other immunosuppressants.

Sirolimus Side effects

  • Common adverse effects include: high triglyceride, decreased platelet and white blood cell counts, anemia, high blood pressure, , diarrhea, pneumonia, and risk of viral infection.
  • Severe allergic reactions, symptoms of high blood sugar, symptoms of infection, symptoms of kidney problems, symptoms of liver problems. unusual bleeding or bruising, unusual lumps, unusual tiredness or weakness, unusual weight changes and vision changes.

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