It decreases the damage to joints and the disability due to rheumatoid arthritis. It restricts the formation of DNA, which is necessary for developing these cells, esp. those in immune system. It suppresses the immune system to decrease inflammation which leads to pain and swelling. It is typically prescribed alone. Leflunomide suppresses immune cells by inhibiting dihydroorotate dehydrogenase, an enzyme that is necessary for the production of DNA and RNA. Without DNA and RNA the cells cannot or exist.

Leflunomide DOSAGE

• It is an oral pill to be taken with or without food, usually once daily.
• A patient might be recommended a high dose for the first three days.
• Dosage is based on your medical condition and response to therapy.

Leflunomide PRECAUTIONS

• It may cause birth defects, therefore avoid pregnancy while on this medication.
• It can cause mild liver irritation, thus, inform your doctor about your medical history related to alcohol, hepatitis, liver diseases and jaundice.
• When taking this medicine, inform your healthcare provider about any other medication you are consuming.

Leflunomide SIDE EFFECTS

• Diarrhoea
• Nausea, stomach pain, indigestion,
• Rash or hair loss.
• Abnormal liver function tests
• Decreased blood cell or platelet counts
• Lowers your body’s ability to fight off some infections.